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Horizon Europe: Update on the 2025 call topics – Health Cluster

Horizon Europe’s Cluster 1 – Health focuses on improving and protecting the health and well-being of people of all ages. It supports the development of new knowledge and innovative solutions to prevent, diagnose, treat, and manage diseases — with attention to gender aspects where relevant.

The programme also invests in health technologies, risk mitigation strategies, and initiatives to promote both general and workplace well-being.

In addition, it aims to strengthen public health systems by making them more cost-effective, equitable, and sustainable, tackling poverty-related diseases, and empowering patients through participation and self-management.

🗂️ Discover the full range of funding opportunities in the 2025 Work Programme – Cluster 1: Health:

Horizon Europe Work Programme 2025 – Health

📅 Deadline for submissions: 16 September 2025

Destination – Tackling diseases and reducing disease burden

  • HORIZON-HLTH-2025-01-DISEASE-01: Testing safety and efficacy of phage therapy for the treatment of antibiotic-resistant bacterial infections
  • HORIZON-HLTH-2025-01-DISEASE-03: Development of antibodies and antibody derived proteins for the prevention and treatment of infectious diseases with epidemic potential
  • HORIZON-HLTH-2025-01-DISEASE-04: Leveraging artificial intelligence for pandemic preparedness and response
  • HORIZON-HLTH-2025-01-DISEASE-05: Support for the functioning of the Global Research Collaboration for Infectious Disease Preparedness (GloPID-R)
  • HORIZON-HLTH-2025-01-DISEASE-06: Implementation research addressing strategies to strengthen health systems for equitable high-quality care and health outcomes in the context of non-communicable diseases (GACD)
  • HORIZON-HLTH-2025-02-DISEASE-02: European partnership fostering a European Research Area (ERA) for health research (Phase 2)

Destination – Ensuring equal access to innovative, sustainable, and high-quality healthcare

  • HORIZON-HLTH-2025-01-CARE-01: End user-driven application of Generative Artificial Intelligence models in healthcare (GenAI4EU)

Destination – Developing and using new tools, technologies and digital solutions for a healthy society

  • HORIZON-HLTH-2025-01-TOOL-01: Enhancing cell therapies with genomic techniques
  • HORIZON-HLTH-2025-01-TOOL-02: Advancing cell secretome-based therapies
  • HORIZON-HLTH-2025-01-TOOL-03: Leveraging multimodal data to advance Generative Artificial Intelligence applicability in biomedical research (GenAI4EU)
  • HORIZON-HLTH-2025-01-TOOL-05: Boosting the translation of biotech research into innovative health therapies

Destination – Maintaining an innovative, sustainable, and competitive EU health industry

  • HORIZON-HLTH-2025-01-IND-01: Optimising the manufacturing of Advanced Therapy Medicinal Products (ATMPs)
  • HORIZON-HLTH-2025-01-IND-02: Digitalisation of conformity assessment procedures of medical devices and in vitro diagnostic medical devices
  • HORIZON-HLTH-2025-01-IND-03: Facilitating the conduct of multinational clinical studies of orphan devices and/or of highly innovative (“breakthrough”) devices